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Expression and Methylation of Mitochondrial Transcription Factor A in Chronic Obstructive Pulmonary Disease Patients with Lung Cancer

BACKGROUND: Apoptosis plays a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD), and this process can be regulated by mitochondrial transcription factor A (mtTFA). Epigenetics is involved in the regulation and modification of the genes involved in lung cancer and COPD....

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Detalhes bibliográficos
Main Authors: Peng, Hong, Yang, Min, Chen, Zhi-yong, Chen, Ping, Guan, Cha-xiang, Xiang, Xu-dong, Cai, Shan, Chen, Yan, Fang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867397/
https://ncbi.nlm.nih.gov/pubmed/24367550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082739
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