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Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas.

The murine lck gene is closely related to a family of cellular protooncogenes and encodes a lymphocyte-specific, membrane-associated protein tyrosine kinase. We and others have demonstrated that the lck gene is rearranged and overexpressed in the murine lymphoma LSTRA, most likely as a result of the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Marth, J D, Disteche, C, Pravtcheva, D, Ruddle, F, Krebs, E G, Perlmutter, R M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3463975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7400
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