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Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas.

The murine lck gene is closely related to a family of cellular protooncogenes and encodes a lymphocyte-specific, membrane-associated protein tyrosine kinase. We and others have demonstrated that the lck gene is rearranged and overexpressed in the murine lymphoma LSTRA, most likely as a result of the...

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Autori principali: Marth, J D, Disteche, C, Pravtcheva, D, Ruddle, F, Krebs, E G, Perlmutter, R M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC386725/
https://ncbi.nlm.nih.gov/pubmed/3463975
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