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Inhibition of Elastin Peptide-Mediated Angiogenic Signaling Mechanism(s) in Choroidal Endothelial Cells by the α6(IV)NC1 Collagen Fragment

PURPOSE. The inhibitory effects and mechanism(s) of type IV collagen α-6 chain–derived noncollagenous domain (α6[IV]NC1 or hexastatin) on elastin-derived peptide (EDP)–activated choroidal endothelial cell migration, kinase signaling, and membrane type 1 metalloproteinase (MT1-MMP) activation are exp...

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Autors principals: Gunda, Venugopal, Verma, Raj Kumar, Sudhakar, Yakkanti Akul
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867182/
https://ncbi.nlm.nih.gov/pubmed/24194191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10870
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