Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphisms.
Simple single-gene disorders in humans can be genetically mapped by using traditional methods of linkage analysis and increasingly abundant restriction fragment length polymorphisms (RFLPs). Many human diseases and traits, however, can be expected to be genetically heterogeneous (i.e., caused by any...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2876423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7353 |
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