Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant

Adoptive immunotherapy with ex vivo expanded T cells is a promising approach to prevent or treat leukemia. Myeloid leukemias express tumor-associated antigens (TAA) that induce antigen-specific cytotoxic T lymphocyte (CTL) responses in healthy individuals. We explored the feasibility of generating T...

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Detalhes bibliográficos
Main Authors: Weber, G, Gerdemann, U, Caruana, I, Savoldo, B, Hensel, NF, Rabin, KR, Shpall, EJ, Melenhorst, JJ, Leen, AM, Barrett, AJ, Bollard, CM
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867129/
https://ncbi.nlm.nih.gov/pubmed/23528871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.66
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