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The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

The compound MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine maleate)] is a potent anticonvulsant that is active after oral administration and whose mechanism of action is unknown. We have detected high-affinity (Kd = 37.2 +/- 2.7 nM) binding sites for [3H]MK-801 in rat bra...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wong, E H, Kemp, J A, Priestley, T, Knight, A R, Woodruff, G N, Iversen, L L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1986
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3529096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.18.7104
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