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The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice
BACKGROUND: Both L-4F, one apolipoprotein A-1 mimetic peptide, and statins can reduce progression of atherosclerosis by different mechanisms. The combination of the two drugs can cause lesion regression by rendering HDL anti-inflammatory. We postulated that combination of L-4F and simvastatin may st...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866605/ https://ncbi.nlm.nih.gov/pubmed/24314261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-180 |
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