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The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice

BACKGROUND: Both L-4F, one apolipoprotein A-1 mimetic peptide, and statins can reduce progression of atherosclerosis by different mechanisms. The combination of the two drugs can cause lesion regression by rendering HDL anti-inflammatory. We postulated that combination of L-4F and simvastatin may st...

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書誌詳細
主要な著者: Ying, Ru, Yuan, Yong, Qin, Ya-Fei, Tian, Di, Feng, Li, Guo, Zhi-Gang, Sun, Yan-Xiang, Li, Ming-Xing
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866605/
https://ncbi.nlm.nih.gov/pubmed/24314261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-180
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