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Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells
The primary cilium regulates cellular signalling including influencing wnt sensitivity by sequestering β-catenin within the ciliary compartment. Topographic regulation of intracellular actin-myosin tension can control stem cell fate of which wnt is an important mediator. We hypothesized that topogra...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866595/ https://ncbi.nlm.nih.gov/pubmed/24346024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03545 |
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