In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133(high) to CD133(low) phenotype and reduces the CD133-related invasiveness

BACKGROUND: Beyond its possible correlation with stemness of tumor cells, CD133/prominin1 is considered an important marker in breast cancer, since it correlates with tumor size, metastasis and clinical stage of triple-negative breast cancers (TNBC), to date the highest risk breast neoplasia. METHOD...

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Detalhes bibliográficos
Main Authors: Brugnoli, Federica, Grassilli, Silvia, Piazzi, Manuela, Palomba, Maria, Nika, Ervin, Bavelloni, Alberto, Capitani, Silvano, Bertagnolo, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866498/
https://ncbi.nlm.nih.gov/pubmed/24330829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-165
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