Dipyridamole analogues as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4)

To identify needed human equilibrative nucleoside transporter 4 (hENT4) inhibitors, we cloned and stably expressed the recombinant protein in PK15NTD (nucleoside transporter deficient) cells, and, investigated its interaction with a series of dipyridamole analogues synthesized in our laboratory. Com...

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Detalhes bibliográficos
Main Authors: Wang, Chunmei, Lin, Wenwei, Playa, Hilaire, Sun, Shan, Cameron, Kenyuna, Buolamwini, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866046/
https://ncbi.nlm.nih.gov/pubmed/24021350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.08.063
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