A GABRA2 Variant Is Associated with Increased Stimulation and ‘High’ Following Alcohol Administration

Aims: Variation in genes encoding GABA(A) receptor subunits has been implicated in the risk of alcohol dependence (AD). We sought to replicate and extend previous findings of a moderating effect of single nucleotide polymorphisms (SNPs) in GABRA2 (which encodes the GABA(A) α-2 subunit) on the subjec...

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Hlavní autoři: Arias, Albert J., Covault, Jonathan, Feinn, Richard, Pond, Timothy, Yang, Bao-Zhu, Ge, Wenjing, Oncken, Cheryl, Kranzler, Henry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Cellular and Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865816/
https://ncbi.nlm.nih.gov/pubmed/24166645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agt163
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