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A Double-blind, Randomized Trial of Sertraline for Alcohol Dependence: Moderation by Age of Onset and 5-HTTLPR Genotype

Late-onset/low vulnerability alcoholics (LOAs) appear to drink less when treated with an SSRI than placebo, whereas early-onset/high vulnerability alcoholics (EOAs) show the opposite effect. We conducted a 12-week, parallel-groups, placebo-controlled trial of the efficacy of sertraline in alcohol de...

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Detalhes bibliográficos
Main Authors: Kranzler, Henry R., Armeli, Stephen, Tennen, Howard, Covault, Jonathan, Feinn, Richard, Arias, Albert J., Pettinati, Helen, Oncken, Cheryl
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130300/
https://ncbi.nlm.nih.gov/pubmed/21192139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0b013e31820465fa
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