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The auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline

The major motor Kinesin-1 provides a key pathway for cell polarization through intracellular transport. Little is known about how Kinesin works in complex cellular surroundings. Several cargos associate with Kinesin via Kinesin light chain (KLC). However, KLC is not required for all Kinesin transpor...

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Autors principals: Williams, Lucy S., Ganguly, Sujoy, Loiseau, Philippe, Ng, Bing Fu, Palacios, Isabel M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865757/
https://ncbi.nlm.nih.gov/pubmed/24257625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.097592
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