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The auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline

The major motor Kinesin-1 provides a key pathway for cell polarization through intracellular transport. Little is known about how Kinesin works in complex cellular surroundings. Several cargos associate with Kinesin via Kinesin light chain (KLC). However, KLC is not required for all Kinesin transpor...

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Bibliografiske detaljer
Main Authors: Williams, Lucy S., Ganguly, Sujoy, Loiseau, Philippe, Ng, Bing Fu, Palacios, Isabel M.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865757/
https://ncbi.nlm.nih.gov/pubmed/24257625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.097592
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