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Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons

Disruption of the Frizzled3 (Fz3) gene leads to defects in axonal growth in the VII(th) and XII(th) cranial motor nerves, the phrenic nerve, and the dorsal motor nerve in fore- and hindlimbs. In Fz3(−/−) limbs, dorsal axons stall at a precise location in the nerve plexus, and, in contrast to the phe...

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Bibliografiska uppgifter
Huvudupphovsmän: Hua, Zhong L, Smallwood, Philip M, Nathans, Jeremy
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865743/
https://ncbi.nlm.nih.gov/pubmed/24347548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01482
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