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RGS17: an emerging therapeutic target for lung and prostate cancers
Ligands for G-protein-coupled receptors (GPCRs) represent approximately 50% of currently marketed drugs. RGS proteins modulate heterotrimeric G proteins and, thus, GPCR signaling, by accelerating the intrinsic GTPase activity of the Gα subunit. Given the prevalence of GPCR targeted therapeutics and...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865709/ https://ncbi.nlm.nih.gov/pubmed/23734683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.91 |
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