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A High Throughput Screen for RGS Proteins Using Steady State Monitoring of Free Phosphate Formation
G-protein coupled receptors are a diverse group that are the target of over 50% of marketed drugs. Activation of these receptors results in the exchange of bound GDP for GTP in the Gα subunit of the heterotrimeric G-protein. The Gα subunit dissociates from the β/γ subunits and both proceed to affect...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633906/ https://ncbi.nlm.nih.gov/pubmed/23626793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062247 |
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