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Antitumor effects of an immunotoxin made with Pseudomonas exotoxin in a nude mouse model of human ovarian cancer.

An immunotoxin composed of Pseudomonas toxin coupled to an antibody to the human transferrin receptor was evaluated for its effect on ovarian cancer. In the tumor model employed, 60 million human ovarian cancer cells were injected into the peritoneal cavity of an immunodeficient nude mouse. By day 5...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: FitzGerald, D J, Willingham, M C, Pastan, I
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6627
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