Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients.

Human lungs bearing cancer (n = 27) exhibited up to an approximately 20-fold [on average approximately 5-fold (P less than 0.005)] increase in the enzyme activity that degrades tryptophan to form formylkynurenine, in comparison with lungs with benign lesions (blebs) (n = 7) taken as controls. On the...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Yasui, H, Takai, K, Yoshida, R, Hayaishi, O
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1986
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2428037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6622
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