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Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with ΔFosB as a Key Mediator

Drugs of abuse induce neuroplasticity in the natural reward pathway, specifically the nucleus accumbens (NAc), thereby causing development and expression of addictive behavior. Recent evidence suggests that natural rewards may cause similar changes in the NAc, suggesting that drugs may activate mech...

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Detalhes bibliográficos
Main Authors: Pitchers, Kyle K., Vialou, Vincent, Nestler, Eric J., Laviolette, Steven R., Lehman, Michael N., Coolen, Lique M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865508/
https://ncbi.nlm.nih.gov/pubmed/23426671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4881-12.2013
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