Notch γ-Secretase Inhibitor Dibenzazepine Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in ApoE Knockout Mice by Multiple Mechanisms

Abdominal aortic aneurysm (AAA) is a life-threatening aortic disease in the elderly. Activation of Notch1 pathway plays a critical role in the development of AAA, but the underlying mechanisms remain poorly understood. In the present study, we explored the mechanisms by which Notch1 activation regul...

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Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Yue-Hong, Li, Fang-Da, Tian, Cui, Ren, Hua-Liang, Du, Jie, Li, Hui-Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865307/
https://ncbi.nlm.nih.gov/pubmed/24358274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083310
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