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The Utility of Shallow RNA-Seq for Documenting Differential Gene Expression in Genes with High and Low Levels of Expression

The sequencing depth necessary for documenting differential gene expression using RNA-Seq has been little explored outside of model systems. In particular, the depth required to analyze large-scale patterns of differential transcription factor expression is not known. The goal of the present study i...

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Detalhes bibliográficos
Main Authors: Atallah, Joel, Plachetzki, David C., Jasper, W. Cameron, Johnson, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865247/
https://ncbi.nlm.nih.gov/pubmed/24358338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084160
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