Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.
Blast formation and mitotic activation of G0-arrested mouse thymocytes were triggered by the addition of concanavalin A plus interleukin 2 (IL-2) to the culture medium. When added alone, Con A induces within 6 hr a complex reprogramming ("priming") that comprises the activation of the IL-2 receptor...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2428033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6430 |
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