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Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.

Blast formation and mitotic activation of G0-arrested mouse thymocytes were triggered by the addition of concanavalin A plus interleukin 2 (IL-2) to the culture medium. When added alone, Con A induces within 6 hr a complex reprogramming ("priming") that comprises the activation of the IL-2...

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Autors principals: Gauchat, J F, Khandjian, E W, Weil, R
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC386517/
https://ncbi.nlm.nih.gov/pubmed/2428033
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