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Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells.

The effect of temperature on secretory protein transport was studied by cell fractionation of rat pancreatic lobules, pulse-labeled in vitro with [35S]methionine and chased for 60 min at 16, 20, or 37 degrees C. Chase at 37 degrees C allowed secretory proteins to reach a zymogen granule fraction, wh...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Saraste, J, Palade, G E, Farquhar, M G
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3462704/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6425
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