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Intrathecal P/Q- and R-type calcium channel blockades on spinal substance P release and c-Fos expression

Intrathecal (IT) studies have shown that several voltage sensitive calcium channels (VSCCs), such as the L-, N- and T-type may play roles in nociception and that of these only the N-type regulates primary afferent substance P (SP) release. However, the actions of other VSCCs at the spinal level are...

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Autors principals: Terashima, Tetsuji, Xu, Qinghao, Yamaguchi, Shigeki, Yaksh, Tony L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865027/
https://ncbi.nlm.nih.gov/pubmed/23810829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.06.018
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