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Structural Insights into Proteasome Activation by the 19S Regulatory Particle

Since its discovery in the late 1970s, the ubiquitin-proteasome system (UPS) has become recognized as the major pathway for regulated cellular proteolysis. Processes ranging from cell cycle control, pathogen resistance, and protein quality control rely on selective protein degradation at the proteas...

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Autori principali: Ehlinger, Aaron, Walters, Kylie J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864829/
https://ncbi.nlm.nih.gov/pubmed/23672618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400417a
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