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Structural basis for heteromeric assembly and perinuclear organization of keratin filaments

There is as yet no high-resolution data regarding the structure and organization of keratin intermediate filaments, which are obligate heteropolymers providing vital mechanical support in epithelia. We report the crystal structure of interacting 2B regions from the central coiled-coil domains of ker...

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Bibliografiske detaljer
Main Authors: Lee, Chang-Hun, Kim, Min-Sung, Chung, Byung Min, Leahy, Daniel J, Coulombe, Pierre A
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864793/
https://ncbi.nlm.nih.gov/pubmed/22705788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2330
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