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Cyclophosphamide Induces an Early Wave of Acrolein-Independent Apoptosis in the Urothelium
PURPOSE: Hemorrhagic cystitis (HC or bladder inflammation) affects a significant number of patients undergoing cyclophosphamide (CP) chemotherapy despite treatment with 2-mercaptoethane sulfonate (Mesna) to inactivate the metabolite acrolein. While the mechanism is unknown, there is clearly acrolein...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864667/ https://ncbi.nlm.nih.gov/pubmed/24353901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/abb.2013.48A2002 |
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