Laddar...

What a Tangled Web We Weave: Emerging Resistance Mechanisms to Inhibition of the Phosphoinositide 3-kinase Pathway

The phosphoinositide 3-kinase (PI3K) pathway is one of the most frequently mutated pathways in cancer, and is actively being pursued as a therapeutic target. Despite the importance of the PI3K pathway in cancer, durable responses to PI3K-pathway targeted therapies are uncommon with monotherapy. Seve...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Klempner, Samuel J., Myers, Andrea P., Cantley, Lewis C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864542/
https://ncbi.nlm.nih.gov/pubmed/24265156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0063
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!