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Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells

Gene targeting by homologous recombination or by sequence-specific nucleases allows the precise modification of genomes and genes to elucidate their functions. Although gene targeting has been used extensively to modify the genomes of mammals, fish, and amphibians, a targeting technology has not bee...

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Bibliographic Details
Main Authors: Schusser, Benjamin, Collarini, Ellen J., Yi, Henry, Izquierdo, Shelley Mettler, Fesler, Jeffrey, Pedersen, Darlene, Klasing, Kirk C., Kaspers, Bernd, Harriman, William D., van de Lavoir, Marie-Cecile, Etches, Robert J., Leighton, Philip A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864345/
https://ncbi.nlm.nih.gov/pubmed/24282302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317106110
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