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Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells
Gene targeting by homologous recombination or by sequence-specific nucleases allows the precise modification of genomes and genes to elucidate their functions. Although gene targeting has been used extensively to modify the genomes of mammals, fish, and amphibians, a targeting technology has not bee...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864345/ https://ncbi.nlm.nih.gov/pubmed/24282302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317106110 |
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