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The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling

Skeletal muscle mass loss and dysfunction have been linked to many diseases. Conversely, resistance exercise, mainly by activating mammalian target of rapamycin complex 1 (mTORC1), promotes skeletal muscle hypertrophy and exerts several therapeutic effects. Moreover, mTORC1, along with peroxisome pr...

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Bibliografiske detaljer
Main Authors: Pérez-Schindler, Joaquín, Summermatter, Serge, Santos, Gesa, Zorzato, Francesco, Handschin, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864298/
https://ncbi.nlm.nih.gov/pubmed/24277823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312039110
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