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Genome-scale metabolic reconstructions of multiple Escherichia coli strains highlight strain-specific adaptations to nutritional environments

Genome-scale models (GEMs) of metabolism were constructed for 55 fully sequenced Escherichia coli and Shigella strains. The GEMs enable a systems approach to characterizing the pan and core metabolic capabilities of the E. coli species. The majority of pan metabolic content was found to consist of a...

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Hlavní autoři: Monk, Jonathan M., Charusanti, Pep, Aziz, Ramy K., Lerman, Joshua A., Premyodhin, Ned, Orth, Jeffrey D., Feist, Adam M., Palsson, Bernhard Ø.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864276/
https://ncbi.nlm.nih.gov/pubmed/24277855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307797110
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