A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA encoding human factor VIII revealed an obvious domain structure for the protein, which can be represented as A1-A2-...

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הוצא לאור ב:	Proc Natl Acad Sci U S A
Principais autores:	Toole, J J, Pittman, D D, Orr, E C, Murtha, P, Wasley, L C, Kaufman, R J
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	National Academy of Sciences 1986
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5939
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