A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA encoding human factor VIII revealed an obvious domain structure for the protein, which can be represented as A1-A2-...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Toole, J J, Pittman, D D, Orr, E C, Murtha, P, Wasley, L C, Kaufman, R J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1986
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5939
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