Polyreactive Antibodies Developing Amidst Humoral Rejection of Human Kidney Grafts Bind Apoptotic Cells and Activate Complement

Antibody Mediated Rejection (AMR) is associated with a variety of graft-reactive antibodies following kidney transplant. To characterize these antibodies, we immortalized 107 B cell clones from a patient with AMR. In a previous study, we showed that six clones were reacting to multiple self-antigens...

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Hauptverfasser: Porcheray, Fabrice, Fraser, James W., Gao, Baoshan, McColl, Aisleen, DeVito, Julie, Dargon, Ian, Helou, Ynes, Wong, Waichi, Girouard, Timothy C., Saidman, Susan L., Colvin, Robert B., Palmisano, Alessandra, Maggiore, Umberto, Vaglio, Augusto, Smith, Rex Neal, Zorn, Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864117/
https://ncbi.nlm.nih.gov/pubmed/23919437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12394
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