Chronic Humoral Rejection of Human Kidney Allografts Is Associated with MMP-2 Accumulation in Podocytes and its Release in the Urine

Chronic humoral rejection (CHR) is an important cause of late graft failures following kidney transplantation. Overall, the pathophysiology of CHR is poorly understood. Matrix metalloproteinase-2 (MMP-2), a type IV collagenase, has been implicated in chronic kidney disease and allograft rejection in...

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Autori principali: Wong, W., DeVito, J., Nguyen, H., Sarracino, D., Porcheray, F., Dargon, I., Pelle, P. D., Collins, A. B., Tolkoff-Rubin, N., Smith, R. N., Colvin, R., Zorn, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805271/
https://ncbi.nlm.nih.gov/pubmed/20977637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03290.x
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