Polyreactive Antibodies Developing Amidst Humoral Rejection of Human Kidney Grafts Bind Apoptotic Cells and Activate Complement

Antibody Mediated Rejection (AMR) is associated with a variety of graft-reactive antibodies following kidney transplant. To characterize these antibodies, we immortalized 107 B cell clones from a patient with AMR. In a previous study, we showed that six clones were reacting to multiple self-antigens...

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Detalhes bibliográficos
Main Authors: Porcheray, Fabrice, Fraser, James W., Gao, Baoshan, McColl, Aisleen, DeVito, Julie, Dargon, Ian, Helou, Ynes, Wong, Waichi, Girouard, Timothy C., Saidman, Susan L., Colvin, Robert B., Palmisano, Alessandra, Maggiore, Umberto, Vaglio, Augusto, Smith, Rex Neal, Zorn, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864117/
https://ncbi.nlm.nih.gov/pubmed/23919437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12394
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