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Induction of SHP2-deficiency in chondrocytes causes severe scoliosis and kyphosis in mice
STUDY DESIGN: Genetic engineering techniques were used to develop an animal model of juvenile scoliosis during a postnatal skeletal-growth stage. OBJECTIVE: To investigate the effect of targeted SHP2 (Src homology-2)-deficiency in chondrocytes on the development of scoliosis during a juvenile growth...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864111/ https://ncbi.nlm.nih.gov/pubmed/23873233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0b013e3182a3d370 |
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