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Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.

Although intensive investigations have been conducted on the allosteric enzyme, aspartate transcarbamoylase, which catalyzes the first committed reaction in the biosynthesis of pyrimidines in Escherichia coli, little is known about the role of individual amino acid residues in catalysis or regulatio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Robey, E A, Wente, S R, Markby, D W, Flint, A, Yang, Y R, Schachman, H K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386411/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3526345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5934
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