Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.

Although intensive investigations have been conducted on the allosteric enzyme, aspartate transcarbamoylase, which catalyzes the first committed reaction in the biosynthesis of pyrimidines in Escherichia coli, little is known about the role of individual amino acid residues in catalysis or regulatio...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Robey, E A, Wente, S R, Markby, D W, Flint, A, Yang, Y R, Schachman, H K
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1986
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3526345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5934
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