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Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: Visualization and quantification of enzyme distribution in the brain

Exogenously delivered butyrylcholinesterase (BChE) has proven to be an efficient bioscavenger against highly toxic organophosphorus poisons and nerve agents. The scavenger properties of BChE when delivered via intramuscular, intravenous, subcutaneous, or intraperitoneal routes are limited to the bod...

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Detalhes bibliográficos
Main Authors: Johnson, Noel D., Duysen, Ellen G., Lockridge, Oksana
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864044/
https://ncbi.nlm.nih.gov/pubmed/19442823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2009.03.001
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