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Visualization of exogenous delivery of nanoformulated butyrylcholinesterase to the central nervous system

Butyrylcholinesterase (BChE) is an efficient bioscavenger of highly toxic organophosphorus poisons and nerve agents. However, BChE administered into the periphery does not provide significant protection of the central nervous system (CNS) due to rejection by the blood brain barrier. In this study, w...

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Bibliografiske detaljer
Main Authors: Gaydess, Andrea, Duysen, Ellen, Li, Yuan, Gilman, Vladimir, Kabanov, Alexander, Lockridge, Oksana, Bronich, Tatiana
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998607/
https://ncbi.nlm.nih.gov/pubmed/20060815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.01.005
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