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Copper(II)-bis-Histidine Coordination Structure in Fibrillar Amyloid-β Peptide Fragment and Model Complexes Revealed by using Electron Spin Echo Envelope Modulation Spectroscopy
Truncated and mutated amyloid-β (Aβ) peptides are models for systematic study of the molecular origins of metal ion effects on Aβ aggregation rates, types of aggregate structures formed, and cytotoxicity, in homogeneous preparations. The 3-D geometry of bis-histidine imidazole coordination of Cu(II)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864031/ https://ncbi.nlm.nih.gov/pubmed/24014287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300236 |
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