Maternal and offspring pools of osteocalcin influence brain development and functions

The powerful regulation of bone mass exerted by the brain suggests the existence of bone-derived signals modulating this regulation or other functions of the brain. We show here that the osteoblast-derived hormone osteocalcin crosses the blood-brain barrier, binds to neurons of the brainstem, midbra...

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Autori principali: Oury, Franck, Khrimian, Lori, Denny, Christine. A., Gardin, Antoine, Chamouni, Alexandre, Goeden, Nick, Huang, Yung-yu, Lee, Hojoon, Srinivas, Prashanth, Gao, Xiao-Bing, Suyama, Shigetomo, Langer, Thomas, Mann, John. J., Horvath, Tamas. L., Bonnin, Alexandre, Karsenty, Gerard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864001/
https://ncbi.nlm.nih.gov/pubmed/24074871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.042
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