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Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
The mouse germ-line presents a unique opportunity to study epigenetic reprogramming in vivo(1). Recently we showed that genome-wide active DNA demethylation in primordial germ cells (PGCs) is linked to changes in nuclear architecture and extensive loss of histone modifications brought about by wides...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863715/ https://ncbi.nlm.nih.gov/pubmed/20595612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1187945 |
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