Inhibiting Myosin-ATPase Reveals Dynamic Range of Mitochondrial Respiratory Control in Skeletal Muscle

Assessment of mitochondrial ADP-stimulated respiratory kinetics in permeabilized skeletal myofibres (PmFB) is increasingly used in clinical diagnostic and basic research settings. However, estimates of the Km for ADP vary considerably (∼20-300 μM) and tend to overestimate respiration at rest. Noting...

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Autors principals: Perry, Christopher G.R., Kane, Daniel A., Lin, Chien-Te, Kozy, Rachel, Cathey, Brook L., Lark, Daniel S., Kane, Constance L., Brophy, Patricia M., Gavin, Timothy P, Anderson, Ethan J., Neufer, P. Darrell
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863643/
https://ncbi.nlm.nih.gov/pubmed/21554250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110366
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