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Synaptic Dysfunction in Prion Diseases: A Trafficking Problem?
Synaptic dysfunction is an important cause of neurological symptoms in prion diseases, a class of clinically heterogeneous neurodegenerative disorders caused by misfolding of the cellular prion protein (PrP(C)). Experimental data suggest that accumulation of misfolded PrP(C) in the endoplasmic retic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863542/ https://ncbi.nlm.nih.gov/pubmed/24369467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/543803 |
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