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Complementary pharmacokinetic measures to further define the profile of once-daily OROS hydromorphone ER during single-dose and steady-state dosing
Conventional measures such as maximum plasma concentration (C(max)) and area under the concentration versus time curve (AUC) may be insufficient to fully describe the pharmacokinetic (PK) profile of extended-release (ER) formulations. A complementary measure, the half-value duration (HVD), correspon...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863398/ https://ncbi.nlm.nih.gov/pubmed/24349945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-625 |
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